The 6 eyes dzi is a good one for reduce sadness and sufferings. It also brings good luck.

In the bouddhist tradition, it has the power to brings liberation of the 6 realms. And it refers to the 6 paramitas ;

Dana Paramita : generosity
Sila Paramita : discipline
ksanti Paramita : patience
Virya : energy sustained effort
Dhyana : meditation and contemplation
Prajna paramita : ultimate wisdom